When developing an industrial fermentation process, the choice of the production organism dictates much of the large-scale fermentation characteristics in addition to the nature of research and development and process development. Well characterized strains with…
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Advanced Fermentation Agitation with Methanotrophs and Other Organisms
By Gregory T. Benz, Lee Enterprises Consulting Introduction Advanced fermentation processes, both aerobic and anaerobic, have been successful on an industrial scale for quite a long time, producing a wide variety of products. In most of…
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Fermentation Expert
A fermentation expert refers to one who assists with the aerobic or anaerobic growth of bacteria, fungi, algae, yeasts, or fungi in glass or steel vessels outfitted with temperature and other environmental controls. Solid-state fermentation…
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Optimum Aspect Ratio for a Fermenter
What is the optimum aspect ratio (or height/diameter ratio) is for a fermenter? The best answer is “it depends”. There is simply no universal optimum. The best design is worked on a case-by-case basis. We…
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Heat Transfer Issues in Mechanically Agitated Fermenters
Heat Transfer Issues in Mechanically Agitated Fermenters? Aerobic fermentation generates a significant amount of heat, which must be removed to maintain a constant temperature. The main heat sources are metabolic heat generation, agitator power input,…
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Industrial Biotech Scale Up
Industrial biotech uses fermentation processes to make biofuels, biobased chemicals, specialty chemicals, nutraceuticals (e.g. cannabidiol), and even ingredients for the recent rise of meat, dairy, and seafood substitutes. Once a company has a bioprocess (including…
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