Optimum Aspect Ratio for a Fermenter

What is the optimum aspect ratio (or height/diameter ratio) is for a fermenter?   The best answer is “it depends”. There is simply no universal optimum. The best design is worked on a case-by-case basis. We can list some factors that affect the optimum. Note that as aspect ratio increases, the following results are produced: The…

Read more

Micro-algae Experts

The history of microalgae finds its roots in the 17th century with the invention of the microscope but scientific and commercial interest in microalgae blossomed in the 20th century and boomed from around 2005 until perhaps 2015 due to oil prices of >>$100 per barrel and growing belief in “Peak Oil”. Being Mother Nature’s most…

Read more

Microbial Fermentation

Microbial fermentation is the growth of a microorganism, usually a bacterium, yeast, or filamentous fungus in a liquid medium to transform one material into another using the microbe’s metabolism as the manufacturing process to result in a commercial product.  That product can be microbial cell mass, a product contained within the microbe, or a product…

Read more

Beverage Fermentation

Beverage fermentation refers to the process by which a microbiological agent, typically fungi (e.g. Saccharomyces spp.) or bacteria (e.g. Lactobacillus spp.), convert a sugar-containing liquid into one which contains alcohol and acid products. Humans have been producing fermented beverages for millennia to prevent spoilage and enhance nutritional quality and flavor. At present, there is a…

Read more

Fermenter Design

Fermenter design encompasses many variables. Some of these include desired oxygen transfer rate, required dissolved oxygen level, maximum allowable partial pressure of CO2 in the exit gas, heat transfer considerations, etc. A key part of the design is to relate mass transfer to agitation and airflow. This is not a trivial task. Developing a broth-specific…

Read more

Techno-Economic Analysis: Synthetic Biology

Techno-economic analysis in synthetic biology is the combination of conceptual process design and production cost estimation activities. Synthetic biology refers to microorganisms that have been genetically altered to produce a foreign molecule as part of their normal metabolism. Products include small organic molecules, (alcohols, fuel-range oils), proteins, and pharmaceutical ingredients. The techno-economic analysis is generally…

Read more